Distributed brain co-processor for tracking spikes, seizures and behaviour during electrical brain stimulation.

ABSTRACT: Early implantable epilepsy therapy devices provided open-loop electrical stimulation without brain sensing, computing, or an interface for synchronized behavioural inputs from patients. Recent epilepsy stimulation devices provide brain sensing but have not yet developed analytics for accurately tracking and quantifying behaviour and seizures. Here we describe a distributed brain co-processor providing an intuitive bi-directional interface between patient, implanted neural stimulation and sensing device, and local and distributed computing resources. Automated analysis of continuous streaming electrophysiology is synchronized with patient reports using a handheld device and integrated with distributed cloud computing resources for quantifying seizures, interictal epileptiform spikes and pat

SUBMITTER: Sladky V 

PROVIDER: S-EPMC9217965 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature