Comparison of Peripheral Blood Regulatory T Cells and Functional Subsets Between Ocular and Generalized Myasthenia Gravis.

ABSTRACT:

Purpose

This study aims to discuss the function mechanism of regulatory T cells and its subsets in the pathogenic process of myasthenia gravis by contracting the activation levels of those cells in peripheral blood among healthy people, patients with ocular myasthenia gravis (oMG) and patients with generalized myasthenia gravis (gMG).

Method

Healthy people, newly diagnosed oMG patients, and gMG patients were enrolled in this study. The percentage of the CD3⁺CD4⁺CD25⁺ Treg cells, CD3⁺CD4⁺CD25⁺Foxp3⁺ Treg cells, CD3⁺CD4⁺CD25⁺Foxp3^hi CD45RA^-aTreg cells, CD3⁺CD4⁺CD25⁺Foxp3^loCD45RA^-n-sTreg cells,

SUBMITTER: Rao J 

PROVIDER: S-EPMC9218215 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature