Construction and validation of a novel prognostic nomogram for patients with metastatic renal cell carcinoma: a SEER-based study.

ABSTRACT:

Objective

We aimed to establish and validate nomograms to evaluate overall survival (OS) and cancer-specific survival (CSS) in patients with metastatic renal cell carcinoma (MRCC).

Methods

Between 2010 and 2015, the clinical information of patients with MRCC was selected using the Surveillance, Epidemiology, and End Results database. Two nomograms were constructed based on Cox regression analysis, and their prediction accuracy was evaluated by concordance index (C-index), receiver operating characteristic (ROC) curve, and decision curve analysis (DCA).

Results

After propensity score matching, there were 568 patients with MRCC in the training group and 568 in the validation group. Multivariate analyses revealed that age, residence, pathology, T stage, N stage, surgery,

SUBMITTER: Lu Z 

PROVIDER: S-EPMC9218494 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature