Genomic Prediction Using LD-Based Haplotypes in Combined Pig Populations.

ABSTRACT: The size of reference population is an important factor affecting genomic prediction. Thus, combining different populations in genomic prediction is an attractive way to improve prediction ability. However, combining multireference population roughly cannot increase the prediction accuracy as well as expected in pig. This may be due to different linkage disequilibrium (LD) pattern differences between population. In this study, we used the imputed whole-genome sequencing (WGS) data to construct LD-based haplotypes for genomic prediction in combined population to explore the impact of different single-nucleotide polymorphism (SNP) densities, variant representation (SNPs or haplotype alleles), and reference population size on the prediction accuracy for reproduction traits. Our results showed

SUBMITTER: Ye H 

PROVIDER: S-EPMC9218795 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature