Cortisol Levels During Acute Illnesses in Children and Adolescents: A Systematic Review.

ABSTRACT:

Importance

Endogenous cortisol levels in children and adolescents during acute illnesses can contribute to the evidence base required to optimize glucocorticoid (GC) stress doses for children and adolescents known to have GC deficiency.

Objective

To identify endogenous cortisol levels during a range of acute illnesses in children and adolescents without GC deficiency from published evidence.

Evidence review

CINAHL, Cochrane Library, Cochrane Database of Systematic Reviews, Embase, and MEDLINE were searched for studies published between January 1, 2000, and June 30, 2020. Two reviewers independently identified relevant studies. Differences were resolved by joint discussion. Inclusion criteria were common acute illnesses, age from 1 month to 18 years, and basal blood co

SUBMITTER: Rezai M 

PROVIDER: S-EPMC9218852 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature