Prognostic Role of Systemic Inflammatory Markers in Patients Undergoing Surgical Resection for Oral Squamous Cell Carcinoma.

ABSTRACT:

Background

A high platelet-lymphocyte ratio (PLR) is a marker of systemic inflammation and, together with the neutrophil-lymphocyte ratio (NLR), is associated with poor outcomes in several cancers. We investigated the prognostic value of PLR and other systemic inflammatory markers, such as NLR, systemic immune-inflammation index (SII), and systemic inflammation response index (SIRI), in oral squamous cell carcinoma (OSCC) patients undergoing surgical resection.

Methods

We derived PLR, NLR, SII, and SIRI from a retrospective chart review of 269 consecutive OSCC patients. The complete blood count examined in the immediate preoperative period was used to compute PLR, NLR, SII, and SIRI. We analyzed the relationship between these systemic inflammatory markers and the clinicopath

SUBMITTER: Cho U 

PROVIDER: S-EPMC9220324 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature