Volatilome Analysis in Prostate Cancer by Electronic Nose: A Pilot Monocentric Study.

ABSTRACT: Urine analysis via an electronic nose provides volatile organic compounds easily usable in the diagnosis of urological diseases. Although challenging and highly expensive for health systems worldwide, no useful markers are available in clinical practice that aim to anticipate prostate cancer (PCa) diagnosis in the early stages in the context of wide population screening. Some previous works suggested that dogs trained to smell urine could recognize several types of cancers with various success rates. We hypothesized that urinary volatilome profiling may distinguish PCa patients from healthy controls. In this study, 272 individuals, 133 patients, and 139 healthy controls participated. Urine samples were collected, stabilized at 37 °C, and analyzed using a commercially available electronic n

SUBMITTER: Filianoti A 

PROVIDER: S-EPMC9220860 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature