Phosphoprotein Detection in Sweat Realized by Intercalation Structure 2D@3D g-C₃N₄@Fe₃O₄ Wearable Sensitive Motif.

ABSTRACT: Abnormal protein phosphorylation in sweat metabolites is closely related to cancer, cardiovascular disease, and other diseases. The real-time monitoring of phosphoproteins in sweat is significant for early monitoring of disease biomarkers. Here, a high-efficiency electrochemical sensor for phosphoprotein in sweat was realized by 2D@3D g-C₃N₄@Fe₃O₄ with intercalation structure. Common phosphoprotein β-Casein was selected to demonstrate the platform's functionalities. The detection limit of g-C₃N₄@Fe₃O₄ could be as low as 9.7 μM, and the detection range was from 0.01 mg/mL to 1 mg/mL. In addition, the sensing platform showed good selectivity, reproducibility, and stability. We also investigated the effect

SUBMITTER: Qiao Y 

PROVIDER: S-EPMC9220892 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature