Filterability of Erythrocytes in Patients with COVID-19.

ABSTRACT: For the first time, the influence of COVID-19 on blood microrheology was studied. For this, the method of filtering erythrocytes through filters with pores of 3.5 μm was used. Filterability was shown to significantly decrease with the increasing severity of the patient's condition, as well as with a decrease in the ratio of hemoglobin oxygen saturation to the oxygen fraction in the inhaled air (SpO₂/FiO₂). The filterability of ≤ 0.65, or its fast decrease during treatment, were indicators of a poor prognosis. Filterability increased significantly with an increase in erythrocyte count, hematocrit and blood concentrations of hemoglobin, albumin, and total protein. The effect of these parameters on the erythrocyte filterability is directly opposite to their effect on blo

SUBMITTER: Prudinnik DS 

PROVIDER: S-EPMC9220947 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature