Management of Extranodal Marginal Zone Lymphoma: Present and Upcoming Perspectives.

ABSTRACT: Extranodal marginal zone lymphoma (EMZL) encompasses a subgroup of non-Hodgkin lymphomas that often present with localized involvement and may manifest in a diversity of organs and tissues. EMZL pathogenesis is in some cases linked to chronic inflammation/infection, which may impose additional diagnostic and clinical challenges. The most studied and established connection is the presence of Helicobacter pylori in gastric EMZL. Due to its heterogeneity of presentation and intricate pathological features, treatment can be complex, and staging systems are decisive for the choice of therapy. Nevertheless, there is no consensus regarding the most suitable staging system, and recommendations vary among different countries. As a rule of thumb, in limited stages, a local therapy with surger

SUBMITTER: Kaddu-Mulindwa D 

PROVIDER: S-EPMC9220961 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature