Young-Onset Gastrointestinal Adenocarcinoma Incidence and Survival Trends in the Northern Territory, Australia, with Emphasis on Indigenous Peoples.

ABSTRACT:

Background and aims

A concerning rise in incidence of young-onset cancers globally led to the examination of trends in incidence and survival of gastrointestinal (GI) adenocarcinomas in the Northern Territory (NT), Australia, over a 28-year period, with a special emphasis on Indigenous peoples.

Methods

This cross-sectional analysis of a prospective longitudinal database, NT Cancer Registry (1990-2017), includes all reported cases of GI (oesophagus, gastric, small intestinal, pancreas, colon, and rectum) adenocarcinomas. Poisson regression was used to estimate incidence ratio ratios, and survival was modelled using Cox proportional hazard models separately for people aged 18-50 years and >50 years.

Results

A total of 1608 cases of GI adenocarcinoma were recorded dur

SUBMITTER: Shepherdson M 

PROVIDER: S-EPMC9220984 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature