Ontology highlight
ABSTRACT:
SUBMITTER: Cesaire M
PROVIDER: S-EPMC9221493 | biostudies-literature | 2022 Jun
REPOSITORIES: biostudies-literature
Césaire Mathieu M Montanari Juliette J Curcio Hubert H Lerouge Delphine D Gervais Radj R Demontrond Pierre P Balosso Jacques J Chevalier François F
Cancers 20220608 12
Survival in unresectable locally advanced stage non-small cell lung cancer (NSCLC) patients remains poor despite chemoradiotherapy. Recently, adjuvant immunotherapy improved survival for these patients but we are still far from curing most of the patients with only a 57% survival remaining at 3 years. This poor survival is due to the resistance to chemoradiotherapy, local relapses, and distant relapses. Several biological mechanisms have been found to be involved in the chemoradioresistance such ...[more]