The Pathological Links between Adiposity and the Carpal Tunnel Syndrome.

ABSTRACT: An association between obesity and carpal tunnel syndrome is found in many epidemiological studies. Therefore, there is a need to evaluate the physiopathological links that could explain the association between these two entities. Ectopic adipose tissue is responsible for metabolic syndrome and inflammation, and is a major risk factor for diabetes and cardiovascular diseases. Taking these elements into consideration, we conducted an extensive literature revision of the subject, considering as ectopic fat-related mechanisms the following: (a) the direct compression and the association with the metabolic syndrome of the fat deposition around the wrist, (b) the insulin resistance, dyslipidemia, inflammatory, and oxidative mechanisms related to the central deposition of the fat, (c) the impair

SUBMITTER: Otelea MR 

PROVIDER: S-EPMC9221759 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature