Nomogram Predicting the Survival of Young-Onset Patients with Colorectal Cancer Liver Metastases.

ABSTRACT: Background: Although the global prevalence of colorectal cancer (CRC) is decreasing, there has been an increase in incidence among young-onset individuals, in whom the disease is associated with specific pathological characteristics, liver metastases, and a poor prognosis. Methods: From 2010 to 2016, 1874 young-onset patients with colorectal cancer liver metastases (CRLM) from the Surveillance, Epidemiology, and End Results (SEER) database were randomly allocated to training and validation cohorts. Multivariate Cox analysis was used to identify independent prognostic variables, and a nomogram was created to predict cancer-specific survival (CSS) and overall survival (OS). Receiver operating characteristic (ROC) curve, C-index, area under the curve (AUC), and calibration curve

SUBMITTER: Cheng X 

PROVIDER: S-EPMC9221975 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature