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Transforming Capillary Alginate Gel (Capgel) into New 3D-Printing Biomaterial Inks.


ABSTRACT: Three-dimensional (3D) printing has great potential for creating tissues and organs to meet shortfalls in transplant supply, and biomaterial inks are key components of many such approaches. There is a need for biomaterial inks that facilitate integration, infiltration, and vascularization of targeted 3D-printed structures. This study is therefore focused on creating new biomaterial inks from self-assembled capillary alginate gel (Capgel), which possesses a unique microstructure of uniform tubular channels with tunable diameters and densities. First, extrusions of Capgel through needles (0.1-0.8 mm inner diameter) were investigated. It was found that Capgel ink extrudes as slurries of fractured and entangled particles, each retaining capillary microstructures, and that extruded line widths

SUBMITTER: Panarello AP 

PROVIDER: S-EPMC9222415 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature