Healthcare provider perspectives on delivering next generation rotavirus vaccines in five low-to-middle-income countries.

ABSTRACT:

Background

Live oral rotavirus vaccines (LORVs) have significantly reduced rotavirus hospitalizations and deaths worldwide. However, LORVs are less effective in low- and middle-income countries (LMICs). Next-generation rotavirus vaccines (NGRVs) may be more effective but require administration by injection or a neonatal oral dose, adding operational complexity. Healthcare providers (HPs) were interviewed to assess rotavirus vaccine preferences and identify delivery issues as part of an NGRV value proposition.

Objective

Determine HP vaccine preferences about delivering LORVs compared to injectable (iNGRV) and neonatal oral (oNGRV) NGRVs.

Methods

64 HPs from Ghana, Kenya, Malawi, Peru, and Senegal were interviewed following a mixed-method guide centered on three vaccine

SUBMITTER: Mooney J 

PROVIDER: S-EPMC9223340 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature