Ontology highlight
ABSTRACT:
SUBMITTER: Fabi M
PROVIDER: S-EPMC9224684 | biostudies-literature | 2022 Jun
REPOSITORIES: biostudies-literature
Fabi Marianna M D'Amico Federica F Turroni Silvia S Andreozzi Laura L Filice Emanuele E Brigidi Patrizia P Lanari Marcello M
Journal of personalized medicine 20220615 6
Kawasaki disease (KD) and Henoch-Schönlein purpura (HSP) are the most frequent vasculitis in childhood. For both, a multifactorial mechanism has been hypothesised, with an abnormal immune response in genetically predisposed children. Gut microbiota (GM) alterations might trigger the hyperimmune reaction. Our aim was to explore the GM in KD and compare it with the GM of HSP and febrile children. Children diagnosed with KD, HSP and non-KD febrile illness (F) were enrolled. GM was profiled by 16S r ...[more]