Antibiotic Prescription and In-Hospital Mortality in COVID-19: A Prospective Multicentre Cohort Study.

ABSTRACT:

Background

Since the beginning of the COVID-19 pandemic, empiric antibiotics (ATBs) have been prescribed on a large scale in both in- and outpatients. We aimed to assess the impact of antibiotic treatment on the outcomes of hospitalised patients with moderate and severe coronavirus disease 2019 (COVID-19).

Methods

We conducted a prospective multicentre cohort study in six clinical hospitals, between January 2021 and May 2021.

Results

We included 553 hospitalised COVID-19 patients, of whom 58% (311/553) were prescribed antibiotics, while bacteriological tests were performed in 57% (178/311) of them. Death was the outcome in 48 patients-39 from the ATBs group and 9 from the non-ATBs group. The patients who received antibiotics during hospitalisation had a higher mortali

SUBMITTER: Pinte L 

PROVIDER: S-EPMC9224767 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature