Intestinal Permeability and Dysbiosis in Female Patients with Recurrent Cystitis: A Pilot Study.

ABSTRACT: Recurrent cystitis (RC) is a common disease, especially in females. Anatomical, behavioral and genetic predisposing factors are associated with the ascending retrograde route, which often causes bladder infections. RC seems to be mainly caused by agents derived from the intestinal microbiota, and most frequently by Escherichia coli. Intestinal contiguity contributes to the etiopathogenesis of RC and an alteration in intestinal permeability could have a major role in RC. The aim of this pilot study is to assess gut microbiome dysbiosis and intestinal permeability in female patients with RC. Patients with RC (n = 16) were enrolled and compared with healthy female subjects (n = 15) and patients with chronic gastrointestinal (GI) disorders (n = 238). We calculated t

SUBMITTER: Graziani C 

PROVIDER: S-EPMC9225239 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature