Differential Expression of CB₁ Cannabinoid Receptor and Cannabinoid Receptor Interacting Protein 1a in Labor.

ABSTRACT: Background: The endocannabinoid system is present in multiple organ systems and is involved in smooth muscle regulation, immune function, neuroendocrine modulation, and metabolism of tissues. Limited data are available regarding the presence and role of this system in reproductive tissues. Components of the endocannabinoid system have been identified in myometrial and placental tissues. However, no study has investigated differential expression of the endocannabinoid system in labor. Objectives: The purpose of this study was to identify and quantify two components of the endocannabinoid system, the CB₁ cannabinoid receptor and cannabinoid receptor interacting protein 1a (CRIP1a) in uterine and placental tissues, and to determine if there is differential expression

SUBMITTER: Kozakiewicz ML 

PROVIDER: S-EPMC9225407 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature