Lower Respiratory Tract Coinfection in the ICU: Prevalence and Clinical Significance of Coinfection Detected via Microbiological Analysis of Bronchoalveolar Lavage Fluid With a Comparison of Invasive Methodologies.

ABSTRACT: Pneumonia remains a significant cause of morbidity and mortality, with increasing interest in the detection and clinical significance of coinfection. Further investigation into the impact of bronchoalveolar lavage (BAL) sampling methodology and efficient clinical utilization of microbiological analyses is needed to guide the management of lower respiratory tract infection in the ICU.

Design

Retrospective observational study.

Setting

ICUs at a single center between August 1, 2012, and January 1, 2018.

Patients

Mechanically ventilated adult patients who underwent BAL testing during an ICU admission were included.

Interventions

None.

Measurements and main results

BAL methodology (bronchoscopic vs nonbronchoscopic), microbiological diagnostic testing, and cli

SUBMITTER: Zelus CS 

PROVIDER: S-EPMC9225485 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature