Genetic medicine is accelerating in Japan.

ABSTRACT:

Background

In 2018, BRACAnalysis® was covered by medical insurance in Japan as a companion diagnostic test for the poly ADP-ribose polymerase inhibitor olaparib. In April 2020, eligibility for BRCA1/2 genetic testing was expanded to the diagnosis of hereditary breast and ovarian cancer syndrome, and medical management including prophylactic surgery and surveillance were covered by public insurance for BRCA1/2 mutation carriers who developed breast or ovarian cancer. The amount of BRCA1/2 genetic testing has been increasing recently, but the number of subjects and the impact of testing for patients' outcomes remain unclear.

Patients and methods

This study explored the potential number of patients who will be eligible for new insurance coverage for BRCA1/2 genetic testing. We

SUBMITTER: Hayashi S 

PROVIDER: S-EPMC9225975 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature