Temporal Grading Index of Functional Network Topology Predicts Pain Perception of Patients With Chronic Back Pain.

ABSTRACT: Chronic back pain (CBP) is a maladaptive health problem affecting the brain function and behavior of the patient. Accumulating evidence has shown that CBP may alter the organization of functional brain networks; however, whether the severity of CBP is associated with changes in dynamics of functional network topology remains unclear. Here, we generated dynamic functional networks based on resting-state functional magnetic resonance imaging (rs-fMRI) of 34 patients with CBP and 34 age-matched healthy controls (HC) in the OpenPain database via a sliding window approach, and extracted nodal degree, clustering coefficient (CC), and participation coefficient (PC) of all windows as features to characterize changes of network topology at temporal scale. A novel feature, named temporal grad

SUBMITTER: Li Z 

PROVIDER: S-EPMC9226296 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature