Case Report: Resting-State Brain-Networks After Near-Complete Hemispherectomy in Adulthood.

ABSTRACT:

Objectives

Understanding the dynamics of reorganized network-level brain functions after hemispherectomy is important for treatment, prognostication, and rehabilitation of brain injury, but also for investigating questions of fundamental neurobehavioral interest: How does the brain promote consciousness despite loss of one hemisphere?

Methods

We studied resting-state functional connectivity (RSFC) in a high-functioning middle-aged man 6 years after functional hemispherectomy following malignant middle cerebral artery infarction, and we compared results to RSFC in 20 healthy controls.

Results

Our analysis indicates increased between-network connectivity for all seven networks examined in the patient's preserved hemisphere, compared to healthy controls, suggesting a shi

SUBMITTER: Fisher PM 

PROVIDER: S-EPMC9226565 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature