Magnetic Resonance Imaging and Its Clinical Correlation in Spinocerebellar Ataxia Type 3: A Systematic Review.

ABSTRACT:

Background

Spinocerebellar ataxia type 3 (SCA3) is a complex cerebrocerebellar disease primarily characterized by ataxia symptoms alongside motor and cognitive impairments. The heterogeneous clinical presentation of SCA3 necessitates correlations between magnetic resonance imaging (MRI) and clinical findings in reflecting progressive disease changes. At present, an attempt to systematically examine the brain-behavior relationship in SCA3, specifically, the correlation between MRI and clinical findings, is lacking.

Objective

We investigated the association strength between MRI abnormality and each clinical symptom to understand the brain-behavior relationship in SCA3.

Methods

We conducted a systematic review on Medline and Scopus to review studies evaluating the brain

SUBMITTER: Yap KH 

PROVIDER: S-EPMC9226753 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature