Relationship between serum lipid level and colorectal cancer: a systemic review and meta-analysis.

ABSTRACT:

Objective

Investigative studies report contradictory results of the relationship between serum lipid levels and the risk of colorectal cancer (CRC). We conducted a meta-analysis of prospective published studies to clarify the relationship between serum lipid and CRC risk.

Design

Systematic review and meta-analysis.

Data sources

PubMed and Embase from inception until December 2020.

Eligibility criteria

We considered prospective cohort and case-control studies that evaluated differences in serum lipid levels with the risk of developing CRC.

Data extraction and synthesis

Two independent reviewers screened and included the studies using standardised electronic data extraction forms. The relative risks of the studies were combined with random-effect and fixed

SUBMITTER: Yang Z 

PROVIDER: S-EPMC9226934 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature