A Novel Necroptosis-Related lncRNA Signature for Predicting Prognosis and Immune Response of Glioma.

ABSTRACT: Glioma is one of the most common intracranial malignancies that plagues people around the world. Despite current improvements in treatment, the prognosis of glioma is often unsatisfactory. Necroptosis is a form of programmed cell death. As research progresses, the role of necroptosis in tumors has gradually attracted the attention of researchers. And lncRNA is regarded as a critical role in the development of cancer. Therefore, this study is aimed at establishing a prognostic model based on necroptosis-associated lncRNAs to accurately assess the prognosis and immune response of patients with glioma. The RNA sequences of glioma patients and normal brain samples were downloaded from The Cancer Genome Atlas (TCGA) and GTEx databases, respectively. The coexpression analysis was performed to id

SUBMITTER: Wu Z 

PROVIDER: S-EPMC9226973 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature