The Effect of Chronic Exposure of Graphene Nanoplates on the Viability and Motility of A549 Cells.

ABSTRACT: Graphene and its derivatives are popular nanomaterials used worldwide in many technical fields and biomedical applications. Due to such massive use, their anticipated accumulation in the environment is inevitable, with a largely unknown chronic influence on living organisms. Although repeatedly tested in chronic in vivo studies, long-term cell culture experiments that explain the biological response to these nanomaterials are still scarce. In this study, we sought to evaluate the biological responses of established model A549 tumor cells exposed to a non-toxic dose of pristine graphene for eight weeks. Our results demonstrate that the viability of the A549 cells exposed to the tested graphene did not change as well as the rate of their growth and proliferation despite nanoplatelet accumula

SUBMITTER: Sestakova B 

PROVIDER: S-EPMC9227066 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature