Cryptococcal Meningitis in Kidney Transplant Recipients: A Two-Decade Cohort Study in France.

ABSTRACT: Cryptococcosis is the third most common cause of invasive fungal infection in solid organ transplant recipients and cryptococcal meningitis (CM) its main clinical presentation. CM outcomes, as well as its clinical features and radiological characteristics, have not yet been considered on a large scale in the context of kidney transplantation (KT). We performed a nationwide retrospective study of adult patients diagnosed with cryptococcosis after KT between 2002 and 2020 across 30 clinical centers in France. We sought to describe overall and graft survival based on whether KT patients with cryptococcosis developed CM or not. Clinical indicators of CNS involvement and brain radiological characteristics were assessed. Eighty-eight cases of cryptococcosis were diagnosed during the study period

SUBMITTER: Tardieu L 

PROVIDER: S-EPMC9227085 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature