Efficacy of Topical Intervention for Recurrent Aphthous Stomatitis: A Network Meta-Analysis.

ABSTRACT: Background and objectives: To compare the efficacy and safety of topical interventions used for recurrent aphthous stomatitis. Materials and Methods: This network meta-analysis was conducted in accordance with the PRISMA statement. We searched four electronic databases, PubMed, Web of Science (WOS), Cochrane Central Register of Controlled Trials and Embase, for randomized controlled trials reporting efficacy and safety data on topical interventions for recurrent aphthous stomatitis. We performed a quality evaluation using a methodology based on the Cochrane Handbook. Two authors independently extracted data on healing effect, size reduction effect, symptom reduction effect, recurrence and safety assessment. Network meta-analysis was then performed using ADDIS and RevMan. R

SUBMITTER: Liu H 

PROVIDER: S-EPMC9227309 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature