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Direct phosphorylation of benzylic C-H bonds under transition metal-free conditions forming sp3C-P bonds.


ABSTRACT: Direct phosphorylation of benzylic C-H bonds was achieved in a biphasic system under transition metal-free conditions. A selective radical/radical sp3C-H/P(O)-H cross coupling was proposed, and various substituted toluenes were applicable. The transformation provided a promising method for constructing sp3C-P bonds.

SUBMITTER: Li Q 

PROVIDER: S-EPMC9227801 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature