Multifunctional PLA/Gelatin Bionanocomposites for Tailored Drug Delivery Systems.

ABSTRACT: A series of bionanocomposites composed of shark gelatin hydrogels and PLA nanoparticles featuring different nanostructures were designed to generate multifunctional drug delivery systems with tailored release rates required for personalized treatment approaches. The global conception of the systems was considered from the desired customization of the drug release while featuring the viscoelastic properties needed for their ease of storage and posterior local administration as well as their biocompatibility and cell growth capability for the successful administration at the biomolecular level. The hydrogel matrix offers the support to develop a direct thermal method to convert the typical kinetic trapped nanostructures afforded by the formulation method whilst avoiding the detrimental nanop

SUBMITTER: Moya-Lopez C 

PROVIDER: S-EPMC9227928 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature