Modulation of Gut Microbiota and Neuroprotective Effect of a Yeast-Enriched Beer.

ABSTRACT: Beer is the most consumed alcoholic beverage worldwide. It is rich in nutrients, and with its microbial component it could play a role in gut microbiota modulation. Conflicting data are currently available regarding the consequences of alcohol and alcohol-containing beverages on dementia and age-associated disorders including Alzheimer's disease (AD), a neurodegeneration characterized by protein aggregation, inflammatory processes and alterations of components of the gut-brain axis. The effects of an unfiltered and unpasteurized craft beer on AD molecular hallmarks, levels of gut hormones and composition of micro/mycobiota were dissected using 3xTg-AD mice. In addition, to better assess the role of yeasts, beer was enriched with the same Saccharomyces cerevisiae strain used for brew

SUBMITTER: Cecarini V 

PROVIDER: S-EPMC9228237 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature