The Future of Uterine Fibroid Management: a More Preventive and Personalized Paradigm.

ABSTRACT: Uterine fibroids are the most common tumors of the female reproductive tract, affecting up to 80% of women. Despite their heavy burden and high prevalence, available medical treatment options are limited and are offered to patients assuming equal responsiveness. These benign tumors are complex, originating from potentially diverse pathobiologic processes, yet they are all managed in a rather standardized symptom-oriented approach that does not take into account the underlying processes. With our increasing understanding of the interplay between genes, epigenetics, individual's lifestyle, and the environment in disease development, uterine fibroid management should be geared towards individualized preventive and treatment options. For example, it seems that some subsets of patients with fib

SUBMITTER: El Sabeh M 

PROVIDER: S-EPMC9228730 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature