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Influenza B: Prospects for the Development of Cross-Protective Vaccines.


ABSTRACT: In this review, we analyze the epidemiological and ecological features of influenza B, one of the most common and severe respiratory infections. The review presents various strategies for cross-protective influenza B vaccine development, including recombinant viruses, virus-like particles, and recombinant proteins. We provide an overview of viral proteins as cross-protective vaccine targets, along with other updated broadly protective vaccine strategies. The importance of developing such vaccines lies not only in influenza B prevention, but also in the very attractive prospect of eradicating the influenza B virus in the human population.

SUBMITTER: Tsybalova LM 

PROVIDER: S-EPMC9228933 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature

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Influenza B: Prospects for the Development of Cross-Protective Vaccines.

Tsybalova Liudmila M LM   Stepanova Liudmila A LA   Ramsay Edward S ES   Vasin Andrey V AV  

Viruses 20220617 6


In this review, we analyze the epidemiological and ecological features of influenza B, one of the most common and severe respiratory infections. The review presents various strategies for cross-protective influenza B vaccine development, including recombinant viruses, virus-like particles, and recombinant proteins. We provide an overview of viral proteins as cross-protective vaccine targets, along with other updated broadly protective vaccine strategies. The importance of developing such vaccine  ...[more]

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