Streptomyces coeruleorubidus as a potential biocontrol agent for Newcastle disease virus.

ABSTRACT:

Background

Newcastle disease virus (NDV) is a severe disease that affects domestic and wild birds. Controlled antibiotics derived from probiotics have been examined as prospective solutions for preserving seroconversion in NDV-vaccinated fowl. In this study, the secondary metabolite "telomycin" was extracted from Streptomyces coeruleorubidus (S. coeruleorubidus) isolated from Egypt's cultivated soil. The structure of telomycin was determined by the elucidation of spectroscopic analysis, including nuclear magnetic resonance (NMR) and mass spectrometry (MS) spectra, and comparison with the literature. The antiviral activity of the secondary metabolite was tested by checking its effect on NDV hemagglutination activity (HA). Moreover, HA of NDV was tested after inoculation of NDV (cont

SUBMITTER: Abdelaziz R 

PROVIDER: S-EPMC9229119 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature