SAPFIR: A webserver for the identification of alternative protein features.

ABSTRACT:

Background

Alternative splicing can increase the diversity of gene functions by generating multiple isoforms with different sequences and functions. However, the extent to which splicing events have functional consequences remains unclear and predicting the impact of splicing events on protein activity is limited to gene-specific analysis.

Results

To accelerate the identification of functionally relevant alternative splicing events we created SAPFIR, a predictor of protein features associated with alternative splicing events. This webserver tool uses InterProScan to predict protein features such as functional domains, motifs and sites in the human and mouse genomes and link them to alternative splicing events. Alternative protein features are displayed as functions of the tr

SUBMITTER: Zhou D 

PROVIDER: S-EPMC9229502 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature