Characterization of Cognitive Function in Survivors of Diffuse Gliomas Using Morphometric Correlation Networks.

ABSTRACT: This pilot study investigates structural alterations and their relationships with cognitive function in survivors of diffuse gliomas. Twenty-four survivors of diffuse gliomas (mean age 44.5 ± 11.5), from whom high-resolution T1-weighted images, neuropsychological tests, and self-report questionnaires were obtained, were analyzed. Patients were grouped by degree of cognitive impairment, and interregional correlations of cortical thickness were computed to generate morphometric correlation networks (MCNs). The results show that the cortical thickness of the right insula (R² = 0.3025, p = 0.0054) was negatively associated with time since the last treatment, and the cortical thickness of the left superior temporal gyrus (R² = 0.2839, p = 0.0107

SUBMITTER: Wang C 

PROVIDER: S-EPMC9229761 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature