Neural correlates of acute post-traumatic dissociation: a functional neuroimaging script-driven imagery study.

ABSTRACT:

Background

Current neurobiological models of post-traumatic stress disorder (PTSD) assume excessive medial frontal activation and hypoactivation of cortico-limbic regions as neural markers of post-traumatic dissociation. Script-driven imagery is an established experimental paradigm that is used to study acute dissociative reactions during trauma exposure. However, there is a scarcity of experimental research investigating neural markers of dissociation; findings from existing script-driven neuroimaging studies are inconsistent and based on small sample sizes.

Aims

The current aim was to identify the neural correlates of acute post-traumatic dissociation by employing the script-driven imagery paradigm in combination with functional magnetic resonance imaging.

Method

Fu

SUBMITTER: Mertens YL 

PROVIDER: S-EPMC9230559 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature