Biochemical and Metabolomic Responses of Antarctic Bacterium Planococcus sp. O5 Induced by Copper Ion.

ABSTRACT: Heavy metal pollution in the Antarctic has gone beyond our imagination. Copper toxicity is a selective pressure on Planococcus sp. O5. We observed relatively broad tolerance in the polar bacterium. The heavy metal resistance pattern is Pb²⁺ > Cu²⁺ > Cd²⁺ > Hg²⁺ > Zn²⁺. In the study, we combined biochemical and metabolomics approaches to investigate the Cu²⁺ adaptation mechanisms of the Antarctic bacterium. Biochemical analysis revealed that copper treatment elevated the activity of antioxidants and enzymes, maintaining the bacterial redox state balance and normal cell division and growth. Metabolomics analysis demonstrated that fatty acids, amino acids, and carbohydrates played dominant roles in copper str

SUBMITTER: Cheng Z 

PROVIDER: S-EPMC9230899 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature