Effect of postmastectomy radiotherapy on T1-2N1M0 triple-negative breast cancer.

ABSTRACT:

Background

The effect of postmastectomy radiotherapy (PMRT) on T1-2N1M0 triple-negative breast cancers (TNBC) remains unclear. The population-based study aimed to investigate the survival outcomes of T1-2N1M0 TNBC patients who underwent PMRT or not.

Methods

We selected 1743 patients with T1-2N1M0 TNBC who underwent mastectomy between 2010 and 2015 through the Surveillance, Epidemiology and End Results (SEER) database. After propensity score matching (PSM), the PMRT and no-PMRT groups consisted of 586 matched patients, respectively. The Kaplan-Meier method was applied to calculate breast cancer-specific survival (BCSS) and cox proportional hazard model was used to determine the prognostic factors of T1-2N1M0 TNBC.

Results

The 5-year BCSS for the PMRT and no-PMRT groups

SUBMITTER: Xia LY 

PROVIDER: S-EPMC9231765 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature