Cortico-amygdalar connectivity and externalizing/internalizing behavior in children with neurodevelopmental disorders.

ABSTRACT:

Background

Externalizing and internalizing behaviors contribute to clinical impairment in children with neurodevelopmental disorders (NDDs). Although associations between externalizing or internalizing behaviors and cortico-amygdalar connectivity have been found in clinical and non-clinical pediatric samples, no previous study has examined whether similar shared associations are present across children with different NDDs.

Methods

Multi-modal neuroimaging and behavioral data from the Province of Ontario Neurodevelopmental Disorders (POND) Network were used. POND participants aged 6-18 years with a primary diagnosis of autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD) or obsessive-compulsive disorder (OCD), as well as typically developing childre

SUBMITTER: Nakua H 

PROVIDER: S-EPMC9232404 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature