Synthesis of (E)-2-(1H-tetrazole-5-yl)-3-phenylacrylenenitrile derivatives catalyzed by new ZnO nanoparticles embedded in a thermally stable magnetic periodic mesoporous organosilica under green conditions.

ABSTRACT: ZnO nanoparticles embedded in a magnetic isocyanurate-based periodic mesoporous organosilica (Fe₃O₄@PMO-ICS-ZnO) were prepared through a modified environmentally-benign procedure for the first time and properly characterized by appropriate spectroscopic and analytical methods or techniques used for mesoporous materials. The new thermally stable Fe₃O₄@PMO-ICS-ZnO nanomaterial with proper active sites and surface area as well as uniform particle size was investigated for the synthesis of medicinally important tetrazole derivatives through cascade condensation and concerted 1,3-cycloaddition reactions as a representative of the Click Chemistry concept. The desired 5-substituted-1H-tetrazole derivatives were smoothly prepared in high to quantitative

SUBMITTER: Safapoor S 

PROVIDER: S-EPMC9232489 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature