Porphyrin as a versatile visible-light-activatable organic/metal hybrid photoremovable protecting group.

ABSTRACT: Photoremovable protecting groups (PPGs) represent one of the main contemporary implementations of photochemistry in diverse fields of research and practical applications. For the past half century, organic and metal-complex PPGs were considered mutually exclusive classes, each of which provided unique sets of physical and chemical properties thanks to their distinctive structures. Here, we introduce the meso-methylporphyrin group as a prototype hybrid-class PPG that unites traditionally exclusive elements of organic and metal-complex PPGs within a single structure. We show that the porphyrin scaffold allows extensive modularity by functional separation of the metal-binding chromophore and up to four sites of leaving group release. The insertion of metal ions can be used to tune their spect

SUBMITTER: Sekhar AR 

PROVIDER: S-EPMC9232598 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature