Autoimmune and viral risk factors are associated with achalasia: A case-control study.

ABSTRACT:

Background

Achalasia is a rare esophageal motility disorder of uncertain etiology. While past studies have indicated that autoimmune conditions and viral infections may be associated with development of achalasia, these associations are yet to be examined in large, population-based studies.

Methods

A matched case-control study was performed using administrative claim data from the IBM MarketScan Commercial Claims and Encounters Database between 2000 and 2019. A history of selected autoimmune conditions and viral infections was assessed using past medical claims. Multivariable conditional logistic regression was used to account for the matched nature of the study design and further control for confounding by demographic and clinical characteristics when reporting adjusted odd

SUBMITTER: Gaber CE 

PROVIDER: S-EPMC9232907 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature