Dataset Information

Healthy Lifestyle Score Including Sleep Duration and Cardiovascular Disease Risk.

ABSTRACT:

Introduction

Although insufficient or prolonged sleep duration is associated with cardiovascular disease, sleep duration is not included in most lifestyle scores. This study evaluates the relationship between a lifestyle score, including sleep duration and cardiovascular disease risk.

Methods

A prospective analysis among 67,250 women in the Nurses' Health Study and 29,114 men in Health Professionals Follow-up Study (1986-2016) was conducted in 2021. Lifestyle factors were updated every 2-4 years using self-reported questionnaires. The traditional lifestyle score was defined as not smoking, having a normal BMI, being physically active (≥30 minutes/day of moderate physical activity), eating a healthy diet, and drinking alcohol in moderation. Low-risk sleep duration, defined as sleeping ≥6 to <8 hours/day, was included as an additional component in the updated lifestyle score. Cox proportional hazard regression models were used to estimate cardiovascular disease risk. The likelihood-ratio test and C-statistics were used to compare both scores.

Results

A total of 11,710 incident cardiovascular disease cases during follow-up were documented. The multivariable-adjusted hazard ratios comparing 6 with 0 low-risk factors in the healthy lifestyle score including sleep duration were 0.17 (95% CI=0.12, 0.23) for cardiovascular disease, 0.14 (95% CI=0.10, 0.21) for coronary heart disease, and 0.20 (95% CI=0.12, 0.33) for stroke. Approximately 66% (95% CI=56%, 75%) of cardiovascular disease, 67% (95% CI=54%, 77%) of coronary heart disease, and 62% (95% CI=42%, 76%) of stroke cases were attributable to poor adherence to a healthy lifestyle including sleep. Adding sleep duration to the score slightly increased the C-statistics from 0.64 (95% CI=0.63, 0.64) to 0.65 (95% CI=0.64, 0.65) (p<0.001).

Conclusions

Adopting a healthy lifestyle including sleep recommendations could substantially reduce the risk of cardiovascular disease in U.S. adults.

SUBMITTER: Guasch-Ferre M

PROVIDER: S-EPMC9232953 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature

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Publications

Healthy Lifestyle Score Including Sleep Duration and Cardiovascular Disease Risk.

Guasch-Ferré Marta M Li Yanping Y Bhupathiraju Shilpa N SN Huang Tianyi T Drouin-Chartier Jean-Philippe JP Manson JoAnn E JE Sun Qi Q Rimm Eric B EB Rexrode Kathryn M KM Willett Walter C WC Stampfer Meir J MJ Hu Frank B FB

American journal of preventive medicine 20220328 1

<h4>Introduction</h4>Although insufficient or prolonged sleep duration is associated with cardiovascular disease, sleep duration is not included in most lifestyle scores. This study evaluates the relationship between a lifestyle score, including sleep duration and cardiovascular disease risk.<h4>Methods</h4>A prospective analysis among 67,250 women in the Nurses' Health Study and 29,114 men in Health Professionals Follow-up Study (1986-2016) was conducted in 2021. Lifestyle factors were updated ...[more]

PMID: 35361505

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Dataset Information

Healthy Lifestyle Score Including Sleep Duration and Cardiovascular Disease Risk.

Introduction

Methods

Results

Conclusions

Publications

Healthy Lifestyle Score Including Sleep Duration and Cardiovascular Disease Risk.

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