Maternal serum persistent organic pollutant exposure and offspring diagnosed ADHD in a national birth cohort.

ABSTRACT:

Background

Evidence implicates environmental factors in attention-deficit/hyperactivity disorder (ADHD) risk. Prenatal exposures to polychlorinated biphenyls (PCBs) and the pesticide metabolite p,p'-dichlorodiphenyl dichloroethylene (DDE) have been linked to lower cognitive ability, increased impulsivity, and attention related deficits in the offspring. However, information on the relationship of these exposures to the risk of clinically diagnosed ADHD is limited.

Objectives

To determine whether prenatal maternal levels of PCBs or DDE are associated with ADHD diagnosis in the offspring.

Methods

The investigation was conducted in the Finnish Prenatal Study of ADHD (FIPS-ADHD), a case-control study nested in a national birth cohort. Cases were born in 1998 or 1999 and d

SUBMITTER: Cheslack-Postava K 

PROVIDER: S-EPMC9232966 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature