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Lab-on-a-Contact Lens: Recent Advances and Future Opportunities in Diagnostics and Therapeutics.


ABSTRACT: The eye is one of the most complex organs in the human body, containing rich and critical physiological information (e.g., intraocular pressure, corneal temperature, and pH) as well as a library of metabolite biomarkers (e.g., glucose, proteins, and specific ions). Smart contact lenses (SCLs) can serve as a wearable intelligent ocular prosthetic device capable of noninvasive and continuous monitoring of various essential physical/biochemical parameters and drug loading/delivery for the treatment of ocular diseases. Advances in SCL technologies and the growing public interest in personalized health are accelerating SCL research more than ever before. Here, the current status and potential of SCL development through a comprehensive review from fabrication to applications to commercialization

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC9233032 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature