Neighborhood characteristics as confounders and effect modifiers for the association between air pollution exposure and subjective cognitive functioning.

ABSTRACT:

Background

Air pollution has been associated with cognitive function in the elderly. Previous studies have not evaluated the simultaneous effect of neighborhood-level socioeconomic status (N-SES), which can be an essential source of bias.

Objectives

We explored N-SES as a confounder and effect modifier in a cross-sectional study of air pollution and subjective cognitive function.

Methods

We included 12,058 participants age 50+ years from the Emory Healthy Aging Study in Metro Atlanta using the Cognitive Function Instrument (CFI) score as our outcome, with higher scores representing worse subjective cognitive function. We estimated 9-year average ambient carbon monoxide (CO), nitrogen oxides (NO_x), and fine particulate matter (PM_2.5) concentration

SUBMITTER: Li Z 

PROVIDER: S-EPMC9233127 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature