ABO blood group and link to COVID-19: A comprehensive review of the reported associations and their possible underlying mechanisms.

ABSTRACT: ABO blood group is long known to be an influencing factor for the susceptibility to infectious diseases, and many studies have been describing associations between ABO blood types and COVID-19 infection and severity, with conflicting findings. This narrative review aims to summarize the literature regarding associations between the ABO blood group and COVID-19. Blood type O is mostly associated with lower rates of SARS-CoV-2 infection, while blood type A is frequently described as a risk factor. Although results regarding the risk of severe outcomes are more variable, blood type A is the most associated with COVID-19 severity and mortality, while many studies describe O blood type as a protective factor for the disease progression. Furthermore, genetic associations with both the risk of in

SUBMITTER: Pereira E 

PROVIDER: S-EPMC9233352 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature